ATOH8 anticorps (C-Term)

N° du produit ABIN499361

L’anticorps Lapin Polyclonal anti-ATOH8 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter ATOH8 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ATOH8 anticorps (C-Term) (ABIN499361)

Antigène: ATOH8 (Atonal Homolog 8 (ATOH8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATOH8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-ATOH8 anticorps

Épitope: C-Term

Specificité: This antibody reacts to ATOH8.

Purification: Affinity chromatography purified via peptide column

Immunogène: ATOH8 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ATOH8.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: ATOH8 antibody can be used for detection of ATOH8 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur ATOH8

Antigène: ATOH8 (Atonal Homolog 8 (ATOH8))

Autre désignation: ATOH8

Sujet: Basic helix-loop-helix (bHLH) transcription factors play important roles in differentiation processes during embryonic development of vertebrates. ATOH8 (MATH6) is a tissue-restricted member of the atonal superfamily of bHLH transcription factors that exhibits 43-57 % identity in the bHLH domain with other mammalian atonal paralogs including the NeuroD and Neurogenin factors. In the mouse, ATOH8 has been implicated in the specification and differentiation of neuronal cell lineages in the brain and may also participate in kidney development. Recent studies show that ATOH8 is a novel component of the pancreatic transcriptional network during embryonic development and suggest a potential role as a modulator of the differentiation program initiated by the pro-endocrine factor Neurog3. It is indispensable for early embryonic development, suggesting a more widespread function for this factor in tissue-specific differentiation processes that are dependent on class II bHLH genes.Synonyms: Helix-loop-helix protein hATH-6, Protein atonal homolog 8, hATH-6, hATH6

ID gène: 84913

NCBI Accession: NP_116216

UniProt: Q96SQ7

Pathways: Regulation of Muscle Cell Differentiation