BCL2L10 anticorps (N-Term)
Aperçu rapide pour BCL2L10 anticorps (N-Term) (ABIN499431)
Antigène
Voir toutes BCL2L10 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody reacts to Bcl-B.
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- Bcl-B antibody was raised against a 16 amino acid peptide from near the amino terminus of human Bcl-B.
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Isotype
- IgG
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Indications d'application
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ELISA. Western Blot: Bcl-B antibody can be used for the detection of Bcl-B at 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
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Autre désignation
- Bcl-2-Like 10
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Sujet
- Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1. Despite its predicted molecular weight, Bcl-B is often at higher molecular weights, presumably due to post-translational modifications.Synonyms: Anti-apoptotic protein NrH, Apoptosis regulator Bcl-B, BCL2L10, BCLB, Bcl-B, Bcl2-L-10, NrH
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ID gène
- 10017
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NCBI Accession
- NP_065129
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UniProt
- Q9HD36
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Pathways
- Positive Regulation of Endopeptidase Activity
Antigène
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