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SH3GLB1 anticorps (C-Term)

SH3GLB1 Reactivité: Humain, Souris WB, IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN499465
  • Antigène Voir toutes SH3GLB1 Anticorps
    SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))
    Épitope
    • 15
    • 8
    • 8
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 54
    • 10
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 50
    • 3
    • 1
    • 1
    Lapin
    Clonalité
    • 52
    • 3
    Polyclonal
    Conjugué
    • 27
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SH3GLB1 est non-conjugé
    Application
    • 41
    • 27
    • 14
    • 13
    • 13
    • 9
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    This anitbody reacts to BIF.
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    BIF antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human BIF.
    Isotype
    IgG
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    Discover our top product SH3GLB1 Anticorps primaire
  • Indications d'application
    ELISA. Western BLot: BIF antibody can be used for the detection of BIF at 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))
    Autre désignation
    Endophilin-B1 (SH3GLB1 Produits)
    Synonymes
    anticorps im:5777505, anticorps wu:fa08f03, anticorps wu:fb13e12, anticorps MGC79086, anticorps sh3glb1, anticorps wu:fc55h11, anticorps wu:fj98d09, anticorps AA409932, anticorps AI314629, anticorps AU015566, anticorps Bif-1, anticorps mKIAA0491, anticorps PPP1R70, anticorps dJ612B15.2, anticorps SH3-domain GRB2-like endophilin B1b, anticorps SH3 domain GRB2 like, endophilin B1 S homeolog, anticorps SH3 domain GRB2 like, endophilin B1, anticorps SH3 domain containing GRB2 like, endophilin B1, anticorps SH3-domain GRB2-like endophilin B1a, anticorps SH3-domain GRB2-like B1 (endophilin), anticorps SH3 domain -containing GRB2-like endophilin B1, anticorps SH3 domain containing GRB2 like endophilin B1, anticorps sh3glb1b, anticorps sh3glb1.S, anticorps sh3glb1, anticorps SH3GLB1, anticorps sh3glb1a, anticorps Sh3glb1
    Sujet
    Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells and is caused by the activation of proteolytic enzymes termed caspases. Proteins that comprise the Bcl-2 family such as Bax appear to control the activation of these enzymes. Bax activity was found to be regulated by its association with Bax-interacting factor 1 (BIF), a member of the endophilin B family that is associated with intracellular membranes.. Following this interaction, Bax undergoes a conformational change and translocates to mitochondrial membranes. The Bax/BIF interaction appears to be enhanced by apoptotic stimuli, suggesting that BIF acts as the trigger to activate Bax, and as suppression of BIF promoted HeLa cell colony formation in soft agar, it may have a role in the suppression of cancer progression. At least two isoforms of BIF are known to exist.Synonyms: BIF1, Bax-interacting factor 1, Bif-1, KIAA0491, SH3 domain-containing GRB2-like protein B1, SH3GLB1
    ID gène
    51100
    UniProt
    Q9Y371
    Pathways
    Autophagy
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