CXCR6 anticorps (N-Term)
Aperçu rapide pour CXCR6 anticorps (N-Term) (ABIN499487)
Antigène
Voir toutes CXCR6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- Bonzo antibody was raised against a peptide corresponding to amino acids near the amino terminus of human Bonzo/STRL33. The sequence of this peptide differs from those of African green monkey and pig-tailed macaque by one or two amino acids, respectively.
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- Human Bonzo (N-Terminus 2) Peptide
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Isotype
- IgG
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Indications d'application
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ELISA. Western Blot: Bonzo antibody can be used for detection of Bonzo at 1/500 dilution. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
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Autre désignation
- CD186 / CXCR6
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Sujet
- Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor (1-4). Bonzo/STRL33 serves as coreceptor for SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.Synonyms: BONZO, CDw186, CXC-R6, CXCR-6, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, STRL33, TYMSTR
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ID gène
- 10663
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NCBI Accession
- NP_006555
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UniProt
- O00574
Antigène
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