BUB1 anticorps (N-Term)
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- Antigène Voir toutes BUB1 Anticorps
- BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BUB1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Specificité
- This antibody reacts to Bub1.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Bub1 antibody was raised against a 19 amino acid peptide from near the amino terminus of human Bub1.
- Isotype
- IgG
- Top Product
- Discover our top product BUB1 Anticorps primaire
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- Indications d'application
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ELISA. Western Blot: Bub1 antibody can be used for detection of bub1 at 2 - 4 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))
- Autre désignation
- BUB1A (BUB1 Produits)
- Synonymes
- anticorps bub1a, anticorps bub1l, anticorps hbub1, anticorps xbub1, anticorps BUB1A, anticorps BUB1L, anticorps hBUB1, anticorps AL022991, anticorps Bub1a, anticorps C80208, anticorps D2Xrf87, anticorps BUB1 mitotic checkpoint serine/threonine kinase, anticorps BUB1, mitotic checkpoint serine/threonine kinase, anticorps BUB1, anticorps bub1, anticorps Bub1
- Sujet
- Bub1 was initially identified as the mammalian homolog to the yeast protein through a cDNA screen. Bub1 encodes a kinase involved in the formation of the spindle checkpoint, an important mechanism that ensures high fidelity mitotic chromosome segregation. It is thought to be required for assembly of a functional inner centromere, sister chromatid cohesion via targeting of the Shugoshim protein and metaphase congression. Bub1 functions by phosphorylating cdc20, a member of the mitotic checkpoint complex and activating the spindle checkpoint. A related protein kinase Bub3 interacts with Bub1 and targets it to kinetochores prior to chromosome alignment. Mutations in bub1 have been associated with aneuploidy and several forms of cancer.Synonyms: BUB1L, Mitotic checkpoint serine/threonine-protein kinase BUB1
- ID gène
- 699
- UniProt
- O43683
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