Calpain 6 anticorps (C-Term)

N° du produit ABIN499521

Cet anticorps anti-Calpain 6 est un anticorps Lapin Polyclonal détectant Calpain 6 dans WB, IHC (p) et EIA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Calpain 6 anticorps (C-Term) (ABIN499521)

Antigène: Calpain 6 (CAPN6)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calpain 6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Calpain 6 anticorps

Épitope: C-Term

Specificité: This antibody reacts to CAPN6.

Purification: Affinity chromatography purified via peptide column

Immunogène: CAPN6 antibody was raised against a 18 amino acid peptide from near the carboxy terminus of human CAPN6.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CAPN6 antibody can be used for the detection of StrepII at 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur Calpain 6

Antigène: Calpain 6 (CAPN6)

Autre désignation: Calpain-6

Sujet: Calpains make up a ubiquitously expressed, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. This large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes as their activation can be triggered by calcium influx and oxidative stress. Calpain 6 (CAPN6) is most similar to Calpain 5, the C-terminal region of CAPN6 lacks homology to the calmodulin-like domain of other vertebrate calpains. CAPN6 is thought to be involved in the regulation of microtubule dynamics and cytoskeletal organization. CAPN6 has also been recently identified as an HIV dependency factor (HDF), suggesting that CAPN6 may be an important drug target in HIV treatment.Synonyms: CALPM, CANPX, CAPN6, Calpain-like protease X-linked, Calpamodulin

ID gène: 827

NCBI Accession: NP_055104

UniProt: Q9Y6Q1