CADPS2 anticorps (Center)

N° du produit ABIN499527

Cet anticorps anti-CADPS2 est un anticorps Lapin Polyclonal détectant CADPS2 dans WB, EIA et IHC (p). Adapté pour Humain, Rat et Souris.

Aperçu rapide pour CADPS2 anticorps (Center) (ABIN499527)

Antigène: CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CADPS2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CADPS2 anticorps

Épitope: Center

Specificité: This antibody reacts to CAPS2.

Purification: Affinity chromatography purified via peptide column

Immunogène: CAPS2 antibody was raised against a 19 amino acid peptide near the center of the human CAPS2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CAPS2 antibody can be used for detection of CAPS2 at 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CADPS2

Antigène: CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))

Autre désignation: CADPS2 / CAPS2

Sujet: CAPS2 and the related protein CAPS1 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles, CAPS-deficient neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. Like CAPS1, numerous isoforms of CAPS2 are known to exist. These isoforms show distinct expression patterns in the brain. For example, CAPS2b showed high expression in the developing cerebellum. Furthermore, one version of CAPS2 mRNA that lacks exon 3 is detected in some autistic patients, suggesting that the differential expression pattern of CAPS2 is involved in neuronal development. This CAPS2 antibody is predicted to be specific to CAPS2 and not recognize CAPS1.Synonyms: Calcium-dependent activator protein for secretion 2, Calcium-dependent secretion activator 2, KIAA1591

ID gène: 93664

NCBI Accession: NP_060424

UniProt: Q86UW7

Pathways: Synaptic Vesicle Exocytosis