CCDC134 anticorps (N-Term)

N° du produit ABIN499587

Cet anticorps anti-CCDC134 Polyclonal Lapin (ABIN499587) détecte spécifiquement CCDC134 dans WB, IHC (p) et EIA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CCDC134 anticorps (N-Term) (ABIN499587)

Antigène: CCDC134 (Coiled-Coil Domain Containing 134 (CCDC134))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC134 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-CCDC134 anticorps

Épitope: N-Term

Specificité: This antibody reacts to CCDC134.

Purification: Affinity chromatography purified via peptide column

Immunogène: CCDC134 antibody was raised against a 17 amino acid peptide near the amino terminus of human CCDC134.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CCDC134 antibody can be used for detection of CCDC134 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CCDC134

Antigène: CCDC134 (Coiled-Coil Domain Containing 134 (CCDC134))

Autre désignation: CCDC134

Sujet: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.Synonyms: Coiled-coil domain-containing protein 134

ID gène: 79879

NCBI Accession: NP_079097

UniProt: Q9H6E4