ABL2 anticorps (AA 935-1050) (AbBy Fluor® 680)

N° du produit ABIN4995903

Cet anticorps Lapin Polyclonal détecte spécifiquement ABL2 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour ABL2 anticorps (AA 935-1050) (AbBy Fluor® 680) (ABIN4995903)

Antigène: ABL2

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABL2 est conjugé à/à la AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-ABL2 anticorps (AbBy Fluor® 680)

Épitope: AA 935-1050

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ABL2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ABL2

Antigène: ABL2

Autre désignation: ABL2

Sujet:

Synonyms: Abelson murine leukemia viral oncogene homolog 2, Abelson related gene protein, Tyrosine kinase ARG, ABLL,ARG,Tyrosine protein kinase ABL2, v abl Abelson murine leukemia viral oncogene homolog 2, ABL2_HUMAN, Abelson tyrosine-protein kinase 2, Tyrosine-protein kinase ARG.

Background: ABL2 (or ARG) is a nonreceptor cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of ABL1 and ABL2 includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. It is involved in translocation with the ETV6 gene in human leukemia and has an altered expression in several human carcinomas. Two isoforms of ABL2 with different N-termini (1A and 1B) have been identified. The C-terminal domain of ABL2 contains two F-actin-binding sequences that perform a number of actions related to cell morphology and motility by interacting with actin filaments.

ID gène: 27