CDNF anticorps (N-Term)

N° du produit ABIN499611

Cet anticorps anti-CDNF est un anticorps Lapin Polyclonal détectant CDNF dans WB, IHC (p) et EIA. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour CDNF anticorps (N-Term) (ABIN499611)

Antigène: CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDNF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-CDNF anticorps

Épitope: N-Term

Specificité: This antibody reacts to CDNF.

Purification: Affinity chromatography purified via peptide column

Immunogène: CDNF antibody was raised against a 12 amino acid peptide from near the amino terminus of human CDNF.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CDNF antibody can be used for detection of CDNF at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CDNF

Antigène: CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

Autre désignation: CDNF

Sujet: The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6-OHDA)-induced degeneration of dopaminergic neurons in a rat model of Parkinson's disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinson's disease. At least two isoforms of CDNF are known to exist. This antibody does not cross-react with MANF.Synonyms: ARMET-like protein 1, ARMETL1, Cerebral dopamine neurotrophic factor, Conserved dopamine neurotrophic factor

ID gène: 441549

UniProt: Q49AH0