CIDEA anticorps (C-Term)

N° du produit ABIN499625

L’anticorps Lapin Polyclonal anti-CIDEA a été validé pour WB, IHC (p) et EIA. Il convient pour détecter CIDEA dans des échantillons de Humain.

Aperçu rapide pour CIDEA anticorps (C-Term) (ABIN499625)

Antigène: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIDEA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-CIDEA anticorps

Épitope: C-Term

Specificité: CIDE-A antibody was raised against a peptide corresponding to amino acids 200 to 217 of human CIDE-A. It has no cross activity to CIDE-B.

Purification: Affinity chromatography purified via peptide column

Immunogène: Human CIDE-A (C-Terminus) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CIDE-A antibody can be used for detection of CIDE-A at 1/1000 to 1/2000dilution. An approximately 23 kDa band can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CIDEA

Antigène: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Autre désignation: CIDE-A

Sujet: Apoptosis is related to many diseases and induced by a family of cell death receptors. Cell death signals are transduced by DD-, DED-, or CARD-containing molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase DFF40/CAD, which is chaperoned and inhibited by DFF45/ICAD (1-4). DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified (5). CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD (5,6). Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is expressed in many tissues.Synonyms: CIDE A, CIDEA, Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A

ID gène: 1149

UniProt: O60543