CIDEA anticorps (C-Term)

N° du produit ABIN499627

Cet anticorps Lapin Polyclonal détecte spécifiquement CIDEA dans WB, IHC (p) et EIA. Il présente une réactivité envers Souris.

Aperçu rapide pour CIDEA anticorps (C-Term) (ABIN499627)

Antigène: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIDEA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-CIDEA anticorps

Épitope: C-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: Mouse mCIDE-A (C-Terminus) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CIDE-A antibody can be used for detection of CIDE-A at 1/500 to 1/1000dilution. An approximately 25 kDa band can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CIDEA

Antigène: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Autre désignation: CIDE-A

Sujet: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified (1). CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD (1,2). Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-A is expressed in many tissues.Synonyms: CIDE A, CIDEA, Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A

UniProt: O70302