CIDEB anticorps (C-Term)

N° du produit ABIN499629

Cet anticorps anti-CIDEB est un anticorps Lapin Polyclonal détectant CIDEB dans WB et EIA. Adapté pour Souris.

Aperçu rapide pour CIDEB anticorps (C-Term) (ABIN499629)

Antigène: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIDEB est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-CIDEB anticorps

Épitope: C-Term

Specificité: CIDE-B antibody was raised against a peptide corresponding to amino acids 204 to 219 of murine CIDE-B. It has no cross activity to CIDE-A.

Purification: Affinity chromatography purified via peptide column

Immunogène: Mouse mCIDE-B (C-Terminus) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CIDE-B antibody can be used for detection of CIDE-B at 1/500 to 1/1000dilution. An approximately 25 kDa band can be detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CIDEB

Antigène: CIDEB (Cell Death-Inducing DFFA-Like Effector B (CIDEB))

Autre désignation: CIDE-B

Sujet: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified (1).CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD (1,2). Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow (1).Synonyms: CIDE B, CIDEB, Cell Death Activator CIDE-B, Cell Death-Inducing DFFA-Like Effector B

ID gène: 12684

UniProt: O70303