CLIP1 anticorps (C-Term)

N° du produit ABIN499641

Cet anticorps anti-CLIP1 est un anticorps Lapin Polyclonal détectant CLIP1 dans WB, IF et EIA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CLIP1 anticorps (C-Term) (ABIN499641)

Antigène: CLIP1 (CAP-GLY Domain Containing Linker Protein 1 (CLIP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLIP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-CLIP1 anticorps

Épitope: C-Term

Specificité: This antibody reacts to CLIP170.

Purification: Affinity chromatography purified via peptide column

Immunogène: CLIP170 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human CLIP170.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CLIP170 antibody can be used for detection of CLIP170 at 0.5 - 1 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CLIP1

Antigène: CLIP1 (CAP-GLY Domain Containing Linker Protein 1 (CLIP1))

Autre désignation: CLIP1 / Restin

Sujet: CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1. At least two isoforms of CLIP170 are known to exist.Synonyms: CAP-Gly domain-containing linker protein 1, CLIP-170, CYLN1, Cytoplasmic linker protein 1, Cytoplasmic linker protein 170 alpha-2, RSN, Reed-Sternberg intermediate filament-associated protein

ID gène: 6249

NCBI Accession: NP_002947

UniProt: P30622

Pathways: Dynamique des Microtubules