CRMP1 anticorps (Intermediate Domain)

N° du produit ABIN499652

L’anticorps Lapin Polyclonal anti-CRMP1 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter CRMP1 dans des échantillons de Humain et Souris.

Aperçu rapide pour CRMP1 anticorps (Intermediate Domain) (ABIN499652)

Antigène: CRMP1 (Collapsin Response Mediator Protein 1 (CRMP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRMP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-CRMP1 anticorps

Épitope: Intermediate Domain

Specificité: CRMP1 antibody was raised against a 16 amino acid peptide from near the center of human CRMP1.

Purification: Affinity chromatography purified via peptide column

Immunogène: Virus CRMP1 / Collapsin response mediator protein 1 / DRP-1 / dihydropyropyrimidinase- related protein 1 (Intermediate Domain) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CRMP1 antibody can be used for the detection of CRMP1 at 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CRMP1

Antigène: CRMP1 (Collapsin Response Mediator Protein 1 (CRMP1))

Autre désignation: CRMP1 / DPYSL1

Sujet: Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis (1). Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity (2). CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain (3), later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth (4). CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons (5).Synonyms: Collapsin response mediator protein 1, DRP-1, Dihydropyrimidinase-related protein 1, ULIP3, Unc-33-like phosphoprotein 3

ID gène: 1400

UniProt: Q14194