CX3CL1 anticorps (N-Term)

N° du produit ABIN499690

Détail du produit anti-CX3CL1 anticorps

Antigène: CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CX3CL1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes CX3CL1.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to 18 amino acids near the amino terminus of Human CX3CL1

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CX3CL1 antibody can be used for detection of CX3CL1 at 0.5 - 1 mg/mLdilution.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CX3CL1

Antigène: CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))

Autre désignation: Fractalkine / CX3CL1 (CX3CL1 Produits)

Synonymes: anticorps ABCD3, anticorps CX3CL1, anticorps DKFZp459K117, anticorps Cx3c, anticorps Scyd1, anticorps ABCD-3, anticorps C3Xkine, anticorps CXC3, anticorps CXC3C, anticorps NTN, anticorps NTT, anticorps SCYD1, anticorps fractalkine, anticorps neurotactin, anticorps AB030188, anticorps AI848747, anticorps CX3C, anticorps Cxc3, anticorps D8Bwg0439e, anticorps ATP binding cassette subfamily D member 3, anticorps C-X3-C motif chemokine ligand 1, anticorps chemokine (C-X3-C motif) ligand 1, anticorps ABCD3, anticorps CX3CL1, anticorps Cx3cl1, anticorps Abcd3

Sujet: Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-α in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1. CX3CL1 is ofen observed migrating at 80 - 100 kDa in SDS-PAGE, presumably due to post-translational modification.Synonyms: C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, FKN, NTT, Neurotactin, SCYD1, Small-inducible cytokine D1

ID gène: 6376

UniProt: P78423

Pathways: Synaptic Membrane