CX3CR1 anticorps (Extracellular Loop)

N° du produit ABIN499694

L’anticorps Lapin Polyclonal anti-CX3CR1 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter CX3CR1 dans des échantillons de Humain.

Aperçu rapide pour CX3CR1 anticorps (Extracellular Loop) (ABIN499694)

Antigène: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CX3CR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-CX3CR1 anticorps

Épitope: Extracellular Loop

Specificité: CX3CR1 antibody was raised against a peptide corresponding to amino acids in an extracellular loop of human CX3CR1. The sequence is identical to that of rat CX3CR1 and differs from that of mouse CX3CR1 by one amino acid (3,4).

Purification: Affinity chromatography purified via peptide column

Immunogène: Human CX3CR1 (Extracellular Loop) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: CX3CR1 antibody can be used for detection of CX3CR1 at 1/500 dilution. THP-1cell lysate can be used as positive control and an approximately 50 kDa band can bedetected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CX3CR1

Antigène: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Autre désignation: CX3CR1 / GPR13

Sujet: CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively, (1-4). The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine (6). CX3CR1 mediates leukocyte migration and adhesion (5). CX3CR1 is expressed in a variety of human tissues and cell lines (2).Synonyms: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28

ID gène: 1524

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin