DCLK3 anticorps (N-Term)

N° du produit ABIN499720

Cet anticorps Lapin Polyclonal détecte spécifiquement DCLK3 dans WB et EIA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour DCLK3 anticorps (N-Term) (ABIN499720)

Antigène: DCLK3 (Doublecortin-Like Kinase 3 (DCLK3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCLK3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-DCLK3 anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: DCLK3 antibody was raised against a 14 amino acid peptide near the amino terminus of human DCLK3.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1 - 2 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur DCLK3

Antigène: DCLK3 (Doublecortin-Like Kinase 3 (DCLK3))

Autre désignation: Doublecortin-Like Kinase 3

Sujet: DCLK3 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family. DCLK3 mRNA, like that of the homologous DCLK1 and DCLK3, is highly expressed in adult brain, but only DCLK3 transcripts are present in liver and kidney, suggesting that DCLK3 may play other roles than in cortical development. The DCLK proteins are homologous to Doublecortin (DCX), a protein that is mutated in X-linked human lissencephaly. In mouse models where the DCX gene has been disrupted, DCLK1 expression increases slightly and appears to compensate for the loss of DCX, as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization.Synonyms: DCAMKL3, DCDC3C, DCK3, DCLK3, KIAA1765, Serine/threonine-protein kinase DCLK3

ID gène: 85443

NCBI Accession: NP_208382

UniProt: Q9C098