anticorps MGC76180, anticorps MGC80733, anticorps 4931430I01Rik, anticorps AI452351, anticorps PP3051, anticorps mitocalcin, anticorps MST133, anticorps MSTP133, anticorps SWS2, anticorps RGD1559565, anticorps EF-hand domain family member D1, anticorps EF-hand domain family member D1 L homeolog, anticorps EF-hand domain family, member D1, anticorps EF hand domain containing 1, anticorps efhd1, anticorps EFHD1, anticorps efhd1.L, anticorps Efhd1
Sujet
EFHD1, also known as Swiprosin-2 or SWS2, is an EF-hand and coiled-coil-containing adaptor protein identified in a subtractive hybridization study using a neuronal cell line established from the cerebellum of an adult p53-null mouse, however further study indicated no difference in normal mice. Its mRNA is widely expressed, with its expression in brain undetectable at embryonic stages, with increasing levels from postnatal to adult development. In situ hybridization showed expression in neurons but not white matter of the cerebellum and cerebrum. EHFD1 is also highly expressed in testes, ovary, and the collecting ducts of the kidney, suggesting that in non-neuronal cells, EFHD1 may be involved in gametogenesis and water-reabsorbtion.Synonyms: EF-hand domain-containing protein 1, EF-hand domain-containing protein D1, PP3051, SWS2, Swiprosin 2, Swiprosin-2