FEM1B anticorps (C-Term)

N° du produit ABIN499814

Détail du produit anti-FEM1B anticorps

Antigène: FEM1B (Fem-1 Homolog B (FEM1B))

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FEM1B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: F1A alpha antibody was raised against a peptide corresponding to amino acids 609 to 622 of human F1A alpha. This sequence is identical to the corresponding sequence of mouse FEM1b .

Purification: Affinity chromatography purified via peptide column

Immunogène: Human F1A alpha Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 0.5 to 1 μg/mL. An approximately 70 kDa band can be detected. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur FEM1B

Antigène: FEM1B (Fem-1 Homolog B (FEM1B))

Autre désignation: FEM1B (FEM1B Produits)

Synonymes: anticorps F1A-ALPHA, anticorps F1AA, anticorps FEM1-beta, anticorps FEM1B, anticorps mKIAA0396, anticorps fem-1 homolog B, anticorps protein fem-1 homolog B, anticorps fem-1 homolog B L homeolog, anticorps fem-1 homolog b (C. elegans), anticorps feminization 1 homolog b (C. elegans), anticorps FEM1B, anticorps Fem1b, anticorps LOC413692, anticorps fem1b.L, anticorps fem1b

Sujet: Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1b (1,2). F1Aalpha/FEM1beta is the homologue of C. elegans sex determining protein FEM-1 (1,2). FEM-1/F1Aalpha is cleaved by CED-3 and caspase (3). FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1 (3). Overexpression of F1Aalpha induces apoptosis. F1Aalpha is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aalpha is expressed in a variety of human and mouse tissues (1,2)Synonyms: F1A-alpha, F1AA, FEM1-beta, Fem-1-like death receptor-binding protein alpha, KIAA0396, Protein fem-1 homolog B

ID gène: 10116

UniProt: Q9UK73