FAIM anticorps (C-Term)

N° du produit ABIN499820

Détail du produit anti-FAIM anticorps

Antigène: FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAIM est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to FAIM.

Purification: Affinity chromatography purified via peptide column

Immunogène: FAIM antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human FAIM.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur FAIM

Antigène: FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))

Autre désignation: FAIM (FAIM Produits)

Synonymes: anticorps FAIM1, anticorps FAIM, anticorps faim, anticorps zgc:92712, anticorps zgc:92723, anticorps Fas apoptotic inhibitory molecule, anticorps Fas apoptotic inhibitory molecule L homeolog, anticorps Fas apoptotic inhibitory molecule b, anticorps Fas apoptotic inhibitory molecule a, anticorps FAIM, anticorps Faim, anticorps faim, anticorps faim.L, anticorps Tsp_00038, anticorps faimb, anticorps faima

Sujet: The susceptibility of primary splenic B cells to Fas-mediated apoptosis is regulated in a receptor-specific fashion. Terminal effectors of B cell Fas-resistance include the known anti-apoptotic proteins Bcl-xL, FLIP, and a recently identified protein termed FAIM. This molecule is broadly expressed in various tissues and exists in at least three isoforms. It is thought that resistance to Fas killing via increased expression of FAIM protects foreign antigen-specific B cells during interactions with FasL-bearing T cells whereas autoreactive B cells are deleted via Fas-dependent cytotoxicity. More recent results have indicated that FAIM interacts with both Trk and p75 neurotrophin receptor and may play a role in promoting neurite outgrowth in different neuronal systems by a mechanism involving the activation of NF-kappaB and the Ras-ERK pathway.Synonyms: FAIM-1, FAIM1, Fas Apoptotic Inhibitory Molecule 1

ID gène: 55179

NCBI Accession: NP_060617

UniProt: Q9NVQ4