GATA3 anticorps (C-Term)

N° du produit ABIN499877

L’anticorps Lapin Polyclonal anti-GATA3 a été validé pour WB et EIA. Il convient pour détecter GATA3 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GATA3 anticorps (C-Term) (ABIN499877)

Antigène: GATA3 (GATA Binding Protein 3 (GATA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GATA3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-GATA3 anticorps

Épitope: C-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: GATA3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human GATA3.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur GATA3

Antigène: GATA3 (GATA Binding Protein 3 (GATA3))

Autre désignation: GATA3

Sujet: GATA3 is a zinc finger transcription factor that was first recognized as a possible determinant of T cell development. Later studies demonstrated that it is expressed in trophoblast giant cells and regulates trophoblast-specific genes during development. Specifically, GATA3 is selectively expressed in the trophectoderm of the peri-implantation embryo and regulates CDX2, which is required for the transcriptional repression of the POU5F1/Oct4 and NANOG genes and is thus essential for the segregation of the inner cell mass and trophectoderm at the blastocyst stage. Decreased or null-expression expression of GATA3 has also been suggested to play a major role in the development and progression of luminal breast cancer.Synonyms: GATA-3, GATA-binding factor 3, Trans-acting T-cell-specific transcription factor GATA-3

ID gène: 2625

NCBI Accession: NP_001002295

UniProt: P23771

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation