GLE1 anticorps (C-Term)

N° du produit ABIN499892

L’anticorps Lapin Polyclonal anti-GLE1 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter GLE1 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour GLE1 anticorps (C-Term) (ABIN499892)

Antigène: GLE1 (GLE1 RNA Export Mediator (GLE1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLE1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-GLE1 anticorps

Épitope: C-Term

Specificité: This antibody reacts to GLE1.

Purification: Affinity chromatography purified via peptide column

Immunogène: Gle1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Gle1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur GLE1

Antigène: GLE1 (GLE1 RNA Export Mediator (GLE1))

Autre désignation: GLE1 / GLE1L

Sujet: The proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus. Gle1 is an essential mRNA export factor in both human and yeast cells. It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6), stimulates Dbp5, a member of the DEAD-box helicase family, triggering mRNP remodeling and facilitating RNA export from the nucleus. Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease. At least three isoforms of Gle1 are known to exist.Synonyms: GLE1-like protein, Nucleoporin GLE1

ID gène: 2733

NCBI Accession: NP_001003722

UniProt: Q53GS7