Calmodulin 1 anticorps (AA 81-152) (AbBy Fluor® 680)

N° du produit ABIN4998949

L’anticorps Lapin Polyclonal anti-Calmodulin 1 a été validé pour WB, FACS, IF (cc) et IF (p). Il convient pour détecter Calmodulin 1 dans des échantillons de Humain et Rat.

Aperçu rapide pour Calmodulin 1 anticorps (AA 81-152) (AbBy Fluor® 680) (ABIN4998949)

Antigène: Calmodulin 1 (Calm1)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calmodulin 1 est conjugé à/à la AbBy Fluor® 680

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Calmodulin 1 anticorps (AbBy Fluor® 680)

Épitope: AA 81-152

Specificité: This antibody may detect CAMI, CAM2, CAM3

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Calmodulin

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Calmodulin 1

Antigène: Calmodulin 1 (Calm1)

Autre désignation: Calmodulin

Sujet:

Synonyms: CALM 1, CALM 2, CALM 3, CALM, CALM1, CALM2, CALM3, CALML2, Calmodulin 1, Calmodulin1, CAM 1, CAM 2, CAM 3, CaM, CAM I, CAM1, CAM2, CAM3, CAMB, CAMC, CAMI, CAMIII, DD132, PHKD, Phosphorylase kinase delta, Phosphorylase kinase delta subunit, Calmodulin1, Calmodulin 1, Calmodulin-1, Calmodulin2, Calmodulin 2, Calmodulin-2, Calmodulin3, Calmodulin 3, Calmodulin-3.

Background: Calmodulin consists of two glycoproteins, 34 and 39 kDa, sometimes designated epithelial antigen, epithelial specific antigen, and epithelial glycoprotein. The glycoproteins are located on the cell membrane surface and in the cytoplasm of virtually all epithelial cells with the exception of most squamous epithelia, hepatocytes, renal proximal tubular cells, gastric parietal cells and myoepithelial cells. Epithelial Calmodulin is found in the large majority of adenocarcinomas of most sites (50-100 % in various studies, as well as neuroendocrine tumours, including small cell carcinoma. Renal cell carcinoma and hepatocellular carcinoma stain in about 30 % of the cases. Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin Ca(2+) complex are a number of protein kinases and phosphatases. Calmodulin has four functional calcium binding sites.

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling