ACBD3 anticorps (N-Term)

N° du produit ABIN499900

Cet anticorps Lapin Polyclonal détecte spécifiquement ACBD3 dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour ACBD3 anticorps (N-Term) (ABIN499900)

Antigène: ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACBD3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-ACBD3 anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: GOLPH1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human GOLPH1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur ACBD3

Antigène: ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))

Autre désignation: ACBD3

Sujet: GOLPH1, also known as GCP60, was initially identified as a Golgi protein that can interact with the integral membrane protein giantin and is thought to be involved in the maintenance of the Golgi structure. GOLPH1 has also been shown to interact with other Golgi proteins such as Golgin-160, a Golgi protein that can be cleaved by caspases-2, -3, and -7, leading to the nuclear localization of Golgin-160. GOLPH1 interaction with the Golgin-160 fragments is stronger than that with the intact Golgin-160, with its interaction regulated by the oxidation state of Cys-463 within GOLPH1, suggesting that the nuclear localization of the caspase-cleaved Golgin-160 fragments is a highly coordinated event. GOLPH1 has also been found to interact with Numb, a cytosolic signaling protein that mediates asymetric cell division of neural progenitor cells to a daughter progenitor cell and a neuron, suggesting that Golgi fragmentation and reconstitution during the cell cycle differentially regulate Numb signaling through changes in GOLPH1 subcellular distribution and may couple cell fate with cell cycle progression.Synonyms: Acyl-CoA-binding domain-containing protein 3, GOCAP1, GOLPH1, Golgi complex-associated protein 1, Golgi phosphoprotein 1, Golgi resident protein GCP60, PAP7, PBR- and PKA-associated protein 7, Peripheral benzodiazepine receptor-associated protein

ID gène: 64746

NCBI Accession: NP_073572

UniProt: Q9H3P7