GRIK3 anticorps (N-Term)

N° du produit ABIN499926

Cet anticorps anti-GRIK3 Polyclonal Lapin (ABIN499926) détecte spécifiquement GRIK3 dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GRIK3 anticorps (N-Term) (ABIN499926)

Antigène: GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIK3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-GRIK3 anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: Grik3 antibody was raised against a 13 amino acid peptide near the amino terminus of the Human Grik3.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur GRIK3

Antigène: GRIK3 (Glutamate Receptor, Ionotropic, Kainate 3 (GRIK3))

Autre désignation: GRIK3 / GLUR7

Sujet: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik3, also known as glutamate receptor 7, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik3 is highly homologous to the related ionotrophic glutamate receptors Grik2 and Grik1. Grik3 has recently been shown to be an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses as grik3-null mice show significantly reduced short- and long-term synaptic potentiation. Other reports have suggested that different polymorphisms in the Grik3 protein may be associated with neurological defects such as recurrent major depressive disorder and schizophrenia.Synonyms: EAA5, Excitatory amino acid receptor 5, GluR-7, Glutamate receptor 7, Glutamate receptor ionotropic kainate 3

ID gène: 2899

UniProt: Q13003

Pathways: Synaptic Membrane