GSTP1 anticorps (Center)

N° du produit ABIN499938

Détail du produit anti-GSTP1 anticorps

Antigène: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to GSTP1.

Purification: Affinity chromatography purified via peptide column

Immunogène: GSTP1 antibody was raised against a 14 amino acid peptide from near the center of human GSTP1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur GSTP1

Antigène: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Autre désignation: GSTP1 / GST3 (GSTP1 Produits)

Synonymes: anticorps DFN7, anticorps FAEES3, anticorps GST3, anticorps GSTP, anticorps PI, anticorps GST-P, anticorps Gst3, anticorps Gstp, anticorps Gstp2, anticorps gst-Pi, anticorps GstpiB, anticorps glutathione S-transferase P-like, anticorps glutathione S-transferase pi 1, anticorps glutathione S-transferase pi 1 L homeolog, anticorps glutathione S-transferase, pi 1, anticorps LOC100739163, anticorps GSTP1, anticorps Gstp1, anticorps LOC100861197, anticorps gstp1.L

Sujet: Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism (i.e., the metabolism of environmental mutagens and carcinogens) and may play a role in susceptibility to cancer. More recent experiments have suggested that differential expression of GSTP1 also contributes to the sensitivity of xenobiotics in the substantia nigra and may influence the pathogenesis of reactive oxygen species-induced neurological disorders such as Parkinson's disease. CpG island hypermethylation of the GSTP1 promoter leading to the silencing of the GSTP1 gene has also been linked to cancer.Synonyms: FAEES3, GST class-pi, GST pi, GSTP1-1, Glutathione S-transferase P

ID gène: 2950

NCBI Accession: NP_000843

UniProt: P09211

Pathways: Cellular Response to Molecule of Bacterial Origin