GSTP1 anticorps (Center)

N° du produit ABIN499938

Cet anticorps anti-GSTP1 Polyclonal Lapin (ABIN499938) détecte spécifiquement GSTP1 dans WB, IHC (p) et EIA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GSTP1 anticorps (Center) (ABIN499938)

Antigène: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-GSTP1 anticorps

Épitope: Center

Specificité: This antibody reacts to GSTP1.

Purification: Affinity chromatography purified via peptide column

Immunogène: GSTP1 antibody was raised against a 14 amino acid peptide from near the center of human GSTP1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur GSTP1

Antigène: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Autre désignation: GSTP1 / GST3

Sujet: Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism (i.e., the metabolism of environmental mutagens and carcinogens) and may play a role in susceptibility to cancer. More recent experiments have suggested that differential expression of GSTP1 also contributes to the sensitivity of xenobiotics in the substantia nigra and may influence the pathogenesis of reactive oxygen species-induced neurological disorders such as Parkinson's disease. CpG island hypermethylation of the GSTP1 promoter leading to the silencing of the GSTP1 gene has also been linked to cancer.Synonyms: FAEES3, GST class-pi, GST pi, GSTP1-1, Glutathione S-transferase P

ID gène: 2950

NCBI Accession: NP_000843

UniProt: P09211

Pathways: Cellular Response to Molecule of Bacterial Origin