HAX1 anticorps (N-Term)
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- Antigène Voir toutes HAX1 Anticorps
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HAX1 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody reacts to HAX1B.
- Purification
- Affinity chromatography purified via peptide column
- Immunogène
- Hax1b antibody was raised against a 10 amino acid peptide near the amino terminus of human Hax1b.
- Isotype
- IgG
- Top Product
- Discover our top product HAX1 Anticorps primaire
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- Indications d'application
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ELISA. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
- Autre désignation
- HAX1 (HAX1 Produits)
- Synonymes
- anticorps HAX1, anticorps hax1, anticorps HCLSBP1, anticorps HS1BP1, anticorps SCN3, anticorps HAX-1, anticorps Hs1bp1, anticorps HSP1BP-1, anticorps SIG-111, anticorps Silg111, anticorps mHAX-1s, anticorps HCLS1 associated protein X-1, anticorps HCLS1 associated X-1, anticorps HAX1, anticorps hax1, anticorps Hax1
- Sujet
- The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting. At least four isoforms of Hax1 are known to exist. This antibody is predicted to recognize Hax1b.Synonyms: HAX-1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1
- ID gène
- 10456
- NCBI Accession
- NP_001018238
- UniProt
- O00165
- Pathways
- Regulation of Actin Filament Polymerization
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