IL16 anticorps (N-Term)

N° du produit ABIN499974

Cet anticorps anti-IL16 est un anticorps Lapin Polyclonal détectant IL16 dans WB, EIA et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour IL16 anticorps (N-Term) (ABIN499974)

Antigène: IL16 (Interleukin 16 (IL16))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL16 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-IL16 anticorps

Épitope: N-Term

Specificité: This antibody recognizes IL-16.

Purification: Affinity chromatography purified via peptide column

Immunogène: IL-16 antibody was raised against a 20 amino acid peptide near the amino terminus of Human IL-16.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: (1-2 μg/mL). Rat brain tissue lysate can be used as positive control. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur IL16

Antigène: IL16 (Interleukin 16 (IL16))

Autre désignation: Interleukin-16 / IL16

Sujet: IL-16 was initially identified as a chemotactic cytokine, but is now known to possess a wide range of activities. Later studies have more fully characterized IL-16 as an immunomodulatory cytokine that contributes to the regulatory process of CD4+ T cell recruitment and activation at sites of inflammation in association with asthma and several autoimmune diseases. The precursor of IL-16 (pro-IL-16) is thought to be cleaved towards the C-terminal region by Caspase-3, releasing a 20 kDa active form that binds to and signals through CD4. Besides acting as a chemotactic cytokine, IL-16 is thought to also be involved in the regulation of T cell proliferation and multiple infectious, immune-mediated, and autoimmune inflammatory disorders including irritable bowel syndrome, systemic lupus erythematosus, and neurodegenerative disorders. At least two isoforms of IL-16 are known to exist, the longer isoform (also known as NIL-16) is detected only in neurons of the cerebellum and hippocampus. This antibody will only detect the NIL-16 isoform.Synonyms: IL-16, LCF, Lymphocyte chemoattractant factor

ID gène: 3603

NCBI Accession: NP_004504

UniProt: Q14005