FBXO43 anticorps (C-Term)

N° du produit ABIN499982

L’anticorps anti-FBXO43 Polyclonal Lapin est utilisé pour la détection de FBXO43 dans des échantillons de Humain. Il a été validé pour WB et EIA.

Aperçu rapide pour FBXO43 anticorps (C-Term) (ABIN499982)

Antigène: FBXO43 (F-Box Protein 43 (FBXO43))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO43 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-FBXO43 anticorps

Épitope: C-Term

Specificité: IL-1RAcP antibody was raised against a peptide corresponding to amino acids 525 to 540 of human IL-1RAcP, which is identical to those of mouse and rat origins. This polyclonal antibody has no cross activity to other members in the IL-1 receptor family.

Purification: Affinity chromatography purified via peptide column

Immunogène: Human IL-1RAcP (C-Terminus 2) Peptide

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: 1/1000 to 1/2000 dilution. An approximately 66 kDa band can be detected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur FBXO43

Antigène: FBXO43 (F-Box Protein 43 (FBXO43))

Autre désignation: FBXO43

Sujet: The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP) (1). IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NFkappa-B inducing kinae (NIK) and of NF-kappaB, recruits to the IL-1R complex through IL-1RAcP (2). IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP (3,4). Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.Synonyms: EMI2, Endogenous meiotic inhibitor 2, F-box only protein 43, FBP5B

ID gène: 100101275

UniProt: Q8AXF4