STRADB anticorps (Intermediate Domain)
Aperçu rapide pour STRADB anticorps (Intermediate Domain) (ABIN500022)
Antigène
Voir toutes STRADB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Intermediate Domain
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Specificité
- ILPIP antibody was raised against a synthetic peptide corresponding to amino acids near the center of human ILPIP.
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- Human ILPIP (Intermediate Domain) Peptide
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Isotype
- IgG
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Indications d'application
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ELISA. Western Blot: 1 to 2 μg/mL. A 34 kDa band can be detected with positive control. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- STRADB (STE20-Related Kinase Adaptor beta (STRADB))
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Autre désignation
- STRAD beta / ILPIP
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Sujet
- ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family (1). Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1? converting enzyme of Fas-induced apotosis (1,2). This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival (3), suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.Synonyms: ALS2CR2, CALS-21, PRO1038, Pseudokinase ALS2CR2, STE20-related kinase adapter protein beta, STRADB
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ID gène
- 55437
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NCBI Accession
- NP_061041
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UniProt
- Q9C0K7
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Pathways
- AMPK Signaling
Antigène
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