CRIPT anticorps (AA 21-80) (AbBy Fluor® 750)

N° du produit ABIN5000526

Cet anticorps Lapin Polyclonal détecte spécifiquement CRIPT dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour CRIPT anticorps (AA 21-80) (AbBy Fluor® 750) (ABIN5000526)

Antigène: CRIPT (Cysteine-Rich PDZ-Binding Protein (CRIPT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRIPT est conjugé à/à la AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CRIPT anticorps (AbBy Fluor® 750)

Épitope: AA 21-80

Homologie: Human,Mouse,Rat,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CRIPT

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CRIPT

Antigène: CRIPT (Cysteine-Rich PDZ-Binding Protein (CRIPT))

Autre désignation: CRIPT

Sujet:

Synonyms: CRIPT, CRIPT_HUMAN, Cysteine rich interactor of PDZ3, Cysteine rich PDZ binding protein, Cysteine-rich interactor of PDZ three, Cysteine-rich interactor of PDZ3, Cysteine-rich PDZ-binding protein, HSPC139, HSPC139 protein, Hypothetical protein CRIPT, Postsynaptic protein CRIPT.

Background: The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. These proteins are physically and functionally linked to cytoskeletal and/or signaling proteins. CRIPT (for cysteine-rich interactor of PDZ three), a novel postsynaptic protein, binds specifically to the PDZ3 domain of PSD-95/SAP 90. CRIPT induces the recruitment of PSD-95/SAP 90 to microtubules, and it has been shown to bind directly to microtubules, indicating that it may be responsible for cytoskeletal anchoring of PSD-95/SAP 90. CRIPT is widely expressed outside of the brain and is highly conserved from animals to plants suggesting a wider role in regulating cytoskeleton-membrane associations.