CshA-Like Fibrillar Surface Protein C (CRPC) anticorps (AbBy Fluor® 750)

N° du produit ABIN5000569

L’anticorps anti-CshA-Like Fibrillar Surface Protein C Monoclonal Souris est utilisé pour la détection de CshA-Like Fibrillar Surface Protein C dans des échantillons de Humain. Il a été validé pour IF (cc) et WB.

Aperçu rapide pour CshA-Like Fibrillar Surface Protein C (CRPC) anticorps (AbBy Fluor® 750) (ABIN5000569)

Antigène: CshA-Like Fibrillar Surface Protein C (CRPC)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: AbBy Fluor® 750

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Western Blotting (WB)

Clone: C11F2

Détail du produit

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinded CRP protein

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CshA-Like Fibrillar Surface Protein C (CRPC)

Autre désignation: CRPC

Sujet:

Synonyms: C-reactive protein, C Reactive Protein, C reactive protein pentraxin related, CRP, MGC88244, PTX 1, PTX1, C-reactive protein(1-205), CRP_HUMAN, Pentraxin 1.

Background: C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.

ID gène: 1401

UniProt: P02741