CERS6 anticorps (N-Term)

N° du produit ABIN500144

L’anticorps Lapin Polyclonal anti-CERS6 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter CERS6 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CERS6 anticorps (N-Term) (ABIN500144)

Antigène: CERS6 (Ceramide Synthase 6 (CERS6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CERS6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-CERS6 anticorps

Épitope: N-Term

Specificité: This antibody detects LASS6. It is predicted not to cross-react with LASS5.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: LASS6 antibody was raised against a 13 amino acid peptide near the amino terminus of the human LASS6.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur CERS6

Antigène: CERS6 (Ceramide Synthase 6 (CERS6))

Autre désignation: LASS6

Sujet: The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. Like the highly homologous LASS5, LASS6 is also an endoplasmic reticulum, multi-pass membrane protein. LASS6 is also involved in the synthesis of C14, C16 and C18-ceramide, but shows a preference for unsaturated fatty acids. LASS6 is broadly expressed in a wide range of tissues and microarray data suggests that it may play a role in cancer differentiation and early embryonic development. At least two isoforms of LASS6 are known to exist.Synonyms: LAG1 longevity assurance homolog 6

ID gène: 253782

NCBI Accession: NP_982288

UniProt: Q6ZMG9