FAIM2 anticorps (N-Term)

N° du produit ABIN500148

Cet anticorps anti-FAIM2 est un anticorps Lapin Polyclonal détectant FAIM2 dans WB, IHC (p) et EIA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour FAIM2 anticorps (N-Term) (ABIN500148)

Antigène: FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAIM2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-FAIM2 anticorps

Épitope: N-Term

Specificité: This antibody detects FAIM2.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: LFG antibody was raised against a 16 amino acid peptide from near the amino terminus of human LFG.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur FAIM2

Antigène: FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))

Autre désignation: FAIM2

Sujet: Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. LFG is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-? death signal. In this respect, LFG is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. LFG, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. LFG is widely distributed, but highly expressed in the hippocampus and other neural tissues. LFG was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.Synonyms: Fas apoptotic inhibitory molecule 2, KIAA0950, LFG, Protein lifeguard, TMBIM2, Transmembrane BAX inhibitor motif-containing protein 2

ID gène: 23017

UniProt: Q9BWQ8