LGI1 anticorps (Center)
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- Antigène Voir toutes LGI1 Anticorps
- LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))
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Épitope
- Center
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Reactivité
- Souris, Humain, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LGI1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects LGI1 atcenter. It will recognize only the longer isoform. The antibody is predicted to be specific to LGI1 and not recognize other LGI proteins.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Peptide affinity chromatography
- Immunogène
- LGI1 antibody was raised against a 14 amino acid peptide from near the center of human LGI1.
- Isotype
- IgG
- Top Product
- Discover our top product LGI1 Anticorps primaire
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- Indications d'application
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ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS containing 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))
- Autre désignation
- LGI1 / EPT (LGI1 Produits)
- Synonymes
- anticorps ADLTE, anticorps ADPAEF, anticorps ADPEAF, anticorps EPITEMPIN, anticorps EPT, anticorps ETL1, anticorps IB1099, anticorps BB130740, anticorps MGC146600, anticorps LGIa, anticorps fb78h12, anticorps wu:fb78h12, anticorps zgc:65886, anticorps leucine rich glioma inactivated 1, anticorps leucine-rich repeat LGI family, member 1, anticorps leucine-rich, glioma inactivated 1, anticorps leucine-rich, glioma inactivated 1b, anticorps leucine-rich, glioma inactivated 1a, anticorps LGI1, anticorps Lgi1, anticorps lgi1, anticorps lgi1b, anticorps lgi1a
- Sujet
- The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist.Synonyms: Epitempin-1, Leucine-rich glioma-inactivated protein 1
- ID gène
- 9211
- UniProt
- O95970
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