LGI1 anticorps (N-Term)

N° du produit ABIN500152

Détail du produit anti-LGI1 anticorps

Antigène: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Épitope: N-Term

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LGI1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects LGI1 at N-term. It is predicted to be specific to LGI1 and not recognize other LGI proteins.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: LGI1 antibody was raised against a 13 amino acid peptide from near the amino terminus of human LGI1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Two isoforms of LGI1 are known to exist, but the top band seenin the western blot is likely to be non-specific.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur LGI1

Antigène: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Autre désignation: LGI1 / EPT (LGI1 Produits)

Synonymes: anticorps ADLTE, anticorps ADPAEF, anticorps ADPEAF, anticorps EPITEMPIN, anticorps EPT, anticorps ETL1, anticorps IB1099, anticorps BB130740, anticorps MGC146600, anticorps LGIa, anticorps fb78h12, anticorps wu:fb78h12, anticorps zgc:65886, anticorps leucine rich glioma inactivated 1, anticorps leucine-rich repeat LGI family, member 1, anticorps leucine-rich, glioma inactivated 1, anticorps leucine-rich, glioma inactivated 1b, anticorps leucine-rich, glioma inactivated 1a, anticorps LGI1, anticorps Lgi1, anticorps lgi1, anticorps lgi1b, anticorps lgi1a

Sujet: The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist.Synonyms: Epitempin-1, Leucine-rich glioma-inactivated protein 1

ID gène: 9211

UniProt: O95970