LGI2 anticorps (N-Term)

N° du produit ABIN500154

Détail du produit anti-LGI2 anticorps

Antigène: LGI2 (Leucine-Rich Repeat LGI Family, Member 2 (LGI2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LGI2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects LGI2 at N-term (only the longest isoform). It is predicted to be specific to LGI2 and not recognize other LGI proteins.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: LGI2 antibody was raised against a 11 amino acid peptide from near the amino terminus of human LGI2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur LGI2

Antigène: LGI2 (Leucine-Rich Repeat LGI Family, Member 2 (LGI2))

Autre désignation: LGI2 (LGI2 Produits)

Synonymes: anticorps LGIL2, anticorps mKIAA1916, anticorps leucine rich repeat LGI family member 2, anticorps leucine-rich repeat LGI family, member 2, anticorps leucine-rich repeat LGI family member 2, anticorps leucine-rich repeat LGI family, member 2a, anticorps LGI2, anticorps Lgi2, anticorps lgi2, anticorps lgi2a

Sujet: The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE. Three isoforms of LGI2 are known to exist.Synonyms: KIAA1916, LGI1-like protein 2, LGI2, LGIL2, Leucine-rich glioma-inactivated protein 2, Leucine-rich repeat LGI family member 2

ID gène: 55203

NCBI Accession: NP_060646

UniProt: Q8N0V4