LGI3 anticorps (Center)

N° du produit ABIN500158

Cet anticorps Lapin Polyclonal détecte spécifiquement LGI3 dans WB et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour LGI3 anticorps (Center) (ABIN500158)

Antigène: LGI3 (Leucine-Rich Repeat LGI Family, Member 3 (LGI3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LGI3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-LGI3 anticorps

Épitope: Center

Specificité: This antibody detects LGI3 at center. It will recognize both isoforms. The antibody is predicted to be specific to LGI3 and not recognize other LGI proteins. The observed higher molecular weight band may represent a post-translationally modified form of LGI3.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: LGI3 antibody was raised against a 12 amino acid peptide from near the center of human LGI3.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur LGI3

Antigène: LGI3 (Leucine-Rich Repeat LGI Family, Member 3 (LGI3))

Autre désignation: LGI3

Sujet: The leucine-rich, glioma inactivated gene 3 (LGI3) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI3 have not been found to be associated with ADTLE. LGI3 expression is induced in rat astrocyte cultures by the amyloid beta (Ab) peptide and accumulated on neuronal plasma membranes of aged monkey brains and co-localized with Ab. Two isoforms of LGI3 are known to exist.Synonyms: LGI1-like protein 4, LGI3, LGIL4, Leucine-rich glioma-inactivated protein 3, Leucine-rich repeat LGI family member 3

ID gène: 203190

UniProt: Q8N145