DHX58 anticorps (C-Term)

N° du produit ABIN500164

Cet anticorps Lapin Polyclonal détecte spécifiquement DHX58 dans WB et EIA. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour DHX58 anticorps (C-Term) (ABIN500164)

Antigène: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHX58 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-DHX58 anticorps

Épitope: C-Term

Specificité: This antibody detects DHX58 at C-term.

Purification: Peptide affinity chromatography

Immunogène: LGP2 antibody was raised against a 12 amino acid peptide from near the carboxy terminus of human LGP2.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DHX58

Antigène: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Autre désignation: DHX58

Sujet: Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.Synonyms: ATP-dependent RNA helicase DHX58, ATP-dependent helicase LGP2, D11LGP2E, DHX58, LGP2, Protein D11Lgp2 homolog

ID gène: 79132

UniProt: Q96C10