LRRC19 anticorps (C-Term)

N° du produit ABIN500196

Cet anticorps anti-LRRC19 est un anticorps Lapin Polyclonal détectant LRRC19 dans WB, IF et EIA. Adapté pour Humain et Souris.

Aperçu rapide pour LRRC19 anticorps (C-Term) (ABIN500196)

Antigène: LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC19 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-LRRC19 anticorps

Épitope: C-Term

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinity chromatography

Immunogène: LRRC19 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LRRC19.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur LRRC19

Antigène: LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

Autre désignation: LRRC19

Sujet: LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.Synonyms: Leucine-rich repeat-containing protein 19

ID gène: 64922

NCBI Accession: NP_075052

UniProt: Q9H756