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MAEL anticorps (C-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement MAEL dans WB et EIA. Il présente une réactivité envers Humain, Souris et Rat.
N° du produit ABIN500218

Aperçu rapide pour MAEL anticorps (C-Term) (ABIN500218)

Antigène

Voir toutes MAEL Anticorps
MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Reactivité

Humain, Souris, Rat

Hôte

  • 8
Lapin

Clonalité

  • 8
Polyclonal

Conjugué

  • 4
  • 2
  • 1
  • 1
Cet anticorp MAEL est non-conjugé

Application

  • 7
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Épitope

    • 5
    • 2
    • 1
    • 1
    C-Term

    Réactivité croisée (Details)

    Species reactivity (tested):Human, mouse, rat

    Purification

    Peptide affinity chromatography

    Immunogène

    Maelstrom antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Maelstrom.

    Isotype

    IgG
  • Indications d'application

    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS containing 0.02 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    -20 °C

    Stockage commentaire

    Store the antibody (in aliquots) at -20 °C.
  • Antigène

    MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

    Autre désignation

    MAEL

    Sujet

    The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.Synonyms: Protein maelstrom homolog

    ID gène

    84944

    UniProt

    Q96JY0
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