MAEL anticorps (C-Term)
Aperçu rapide pour MAEL anticorps (C-Term) (ABIN500218)
Antigène
Voir toutes MAEL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
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Purification
- Peptide affinity chromatography
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Immunogène
- Maelstrom antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Maelstrom.
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Isotype
- IgG
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Indications d'application
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store the antibody (in aliquots) at -20 °C.
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- MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))
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Autre désignation
- MAEL
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Sujet
- The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.Synonyms: Protein maelstrom homolog
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ID gène
- 84944
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UniProt
- Q96JY0
Antigène
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