MAK10/NAA35 anticorps (N-Term)
Aperçu rapide pour MAK10/NAA35 anticorps (N-Term) (ABIN500220)
Antigène
Voir toutes MAK10/NAA35 (MAK10) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody detects MAK10 at N-term.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
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Purification
- Peptide affinity chromatography
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Immunogène
- 19 amino acid peptide near the amino terminus of human MAK10
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Isotype
- IgG
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Indications d'application
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- MAK10/NAA35 (MAK10) (MAK10 Homolog, Amino-Acid N-Acetyltransferase Subunit (MAK10))
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Autre désignation
- NAA35 / MAK10
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Sujet
- The MAK10 gene encodes a 733-amino acid protein with several regions of similarity to T cell receptor alpha-subunit V (variable) regions in yeast. The mammalian homologue of yeast MAK10, also known as EGAP, is one subunit of a novel N-terminal acetyltransferase (NAT) that is highly conserved among vertebrate species. It is expressed in a variety of tissues in the developing rat embryo but restricted in expression in the adult, remaining detectable only in tissues undergoing continual cell renewal or in cells responding to pathological injury. The MAK10-NAT complex is an essential regulatory enzyme controlling the function of a subset of proteins required for embryonic growth control and vessel development. This complex functionally co-assembles in mammalian cells to regulate cell proliferation and is essential for embryonic development, at least in part through the regulation of target of rapamycin (TOR) signaling events. At least two isoforms of MAK10 are known to exist.Synonyms: EGAP, Embryonic growth-associated protein homolog, N-alpha-acetyltransferase 35 NatC auxiliary subunit
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ID gène
- 60560
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NCBI Accession
- NP_078911
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UniProt
- Q5VZE5
Antigène
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