MED4 anticorps (C-Term)

N° du produit ABIN500270

L’anticorps Lapin Polyclonal anti-MED4 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter MED4 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour MED4 anticorps (C-Term) (ABIN500270)

Antigène: MED4 (Mediator Complex Subunit 4 (MED4))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-MED4 anticorps

Épitope: C-Term

Specificité: This antibody detects MED4. It only recognizes the largest isoform.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: MED4 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human MED4.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur MED4

Antigène: MED4 (Mediator Complex Subunit 4 (MED4))

Autre désignation: MED4

Sujet: The mediator complex is a multi-protein transcriptional co-activator that is expressed ubiquitously in eukaryotes from yeast to mammals and is required for induction of RNA polymerase II (pol II) transcription by DNA binding transcription factor. One of the proteins in this complex is MED4. This protein has also been shown to be part of the vitamin D receptor interacting complex. MED4 was recently identified as an HIV dependency factor (HDF), suggesting that MED4 may be an important drug target in HIV treatment. At least three isoforms of MED4 are known to exist.Synonyms: ARC36, Activator-recruited cofactor 36 kDa component, DRIP36, HSPC126, Mediator complex 4, Mediator of RNA polymerase II transcription subunit 4, TRAP/SMCC/PC2 subunit p36 subunit, VDRIP, Vitamin D3 receptor-interacting protein complex 36 kDa component

ID gène: 29079

NCBI Accession: NP_054885

UniProt: Q9NPJ6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha