FMR1 anticorps

N° du produit ABIN5002774

L’anticorps Souris Monoclonal anti-FMR1 a été validé pour WB. Il convient pour détecter FMR1 dans des échantillons de Humain.

Aperçu rapide pour FMR1 anticorps (ABIN5002774)

Antigène: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FMR1 est non-conjugé

Application: Western Blotting (WB)

Clone: 8C2

Détail du produit anti-FMR1 anticorps

Réactivité croisée: Humain

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogène: This FMR1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 20-48 amino acids from human FMR1.

Isotype: IgM

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur FMR1

Antigène: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Autre désignation: FMR1

Sujet:

Synonyms: POF, FMRP, POF1, FRAXA, Synaptic functional regulator FMR1, Fragile X mental retardation protein 1, Protein FMR-1, FMR1

Background: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

ID gène: 2332

UniProt: Q06787

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development