METTL7B anticorps (N-Term)
Aperçu rapide pour METTL7B anticorps (N-Term) (ABIN500278)
Antigène
Voir toutes METTL7B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Specificité
- This antibody detects METTL7B at N-term.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse
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Purification
- Peptide affinity chromatography
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Immunogène
- MettL7B antibody was raised against a 13 amino acid peptide near the amino terminus of human MettL7B.
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Isotype
- IgG
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Indications d'application
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ELISA. Western blot: 2 - 4 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- METTL7B (Methyltransferase Like 7B (METTL7B))
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Autre désignation
- METTL7B
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Sujet
- MettL7b belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. This MettL7B antibody is predicted to not cross-react with MettL7A.Synonyms: Methyltransferase-like protein 7B, UNQ594/PRO1180
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ID gène
- 196410
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NCBI Accession
- NP_689850
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UniProt
- Q6UX53
Antigène
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