MINA anticorps (N-Term)

N° du produit ABIN500284

Cet anticorps Lapin Polyclonal détecte spécifiquement MINA dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour MINA anticorps (N-Term) (ABIN500284)

Antigène: MINA (MYC Induced Nuclear Antigen (MINA))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MINA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-MINA anticorps

Épitope: N-Term

Réactivité croisée (Details): Species reactivity (tested):Human, mouse

Purification: Peptide affinty chromatography

Immunogène: MINA antibody was raised against a 15 amino acid peptide near the amino terminus of human MINA.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur MINA

Antigène: MINA (MYC Induced Nuclear Antigen (MINA))

Autre désignation: MYC-Induced Nuclear Antigen

Sujet: MINA is nuclear localized, myc-inducible protein that is thought to play a role in mammalian cell proliferation. Treatment of cancer cells lines such as the colon cancer cell line SW680 with siRNA against MINA inhibits cell growth, demonstrating that MINA may be a potential therapeutic target. MINA regulates several genes related to cell adhesion and metabolism that have also been shown to be regulated by c-Myc, but also regulates other genes whose expression are not modulated by c-Myc such as EGFR, IL-6 and HGF. MINA has also been found to act as a repressor to IL-4 expression in T cells, indicating that it may also play a role in T cell differentiation and genetic variation in T helper type 2 bias.Synonyms: MDIG, MINA, MINA53, Mineral dust-induced gene protein, NO52, Nucleolar protein 52

ID gène: 84864

NCBI Accession: NP_694822

UniProt: Q8IUF8