GALR3 anticorps (AA 1-100) (AbBy Fluor® 750)

N° du produit ABIN5003164

L’anticorps Lapin Polyclonal anti-GALR3 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter GALR3 dans des échantillons de Humain.

Aperçu rapide pour GALR3 anticorps (AA 1-100) (AbBy Fluor® 750) (ABIN5003164)

Antigène: GALR3 (Galanin Receptor 3 (GALR3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GALR3 est conjugé à/à la AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-GALR3 anticorps (AbBy Fluor® 750)

Épitope: AA 1-100

Homologie: Human,Mouse,Rat,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GALR3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GALR3

Antigène: GALR3 (Galanin Receptor 3 (GALR3))

Autre désignation: GALR3

Sujet:

Synonyms: GAL 3R, GAL R3, GAL3 R, GAL3-R, GAL3R, Galanin receptor 3, Galanin receptor-3, Galanin receptor family member 3, Galanin receptor type 3, GALN R3, GALNR 3, GALNR3, GALR 3, GALR-3, Galr3, GALR3_HUMAN.

Background: GALR3 a 368 and 370 amino acid protein in human and rat, respectively, belongs to a family of G protein-coupled receptors that bind the neuropeptide galanin, which is distributed throughout the central and peripheral nervous system, the pituitary gland, the gastrointestinal tract and in the endocrine and exocrine pancreas. GALR3 mRNA is widely distributed, but expressed at low abundance. In human, GALR3 mRNA is highly expressed in the hypothalamus, pituitary and testis, and is expressed to a lesser extent in adrenal gland and pancreas. Rat and human GALR3 co-express with potassium channel subunits GIRK1 and GIRK4. Like GALR1, GALR3 signaling pathways lead to the inhibition of adenylate cyclase and to the activation of potassium channels, which are linked to the regulation of neurotransmitter release. Binding of galanin to galanin receptors results in increased feeding, impaired learning, enhanced opiate analgesia and decreased opiate place preference.

ID gène: 8484

Pathways: cAMP Metabolic Process, Feeding Behaviour