NOL3 anticorps (C-Term)

N° du produit ABIN500371

Détail du produit anti-NOL3 anticorps

Antigène: NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOL3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects NOL3. It will not detect ARC protein.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: Nop30 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human Nop30.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur NOL3

Antigène: NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))

Autre désignation: NOL3 / ARC (NOL3 Produits)

Synonymes: anticorps ARC, anticorps FCM, anticorps MYP, anticorps NOP, anticorps NOP30, anticorps B430311C09Rik, anticorps MYC, anticorps Nop30, anticorps Arc, anticorps nucleolar protein 3, anticorps nucleolar protein 3 (apoptosis repressor with CARD domain), anticorps NOL3, anticorps Nol3

Sujet: Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation. Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and the caspase family of proteases. CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. An alternate splicing isoform of ARC was identified as Nop30. While ARC interacts with caspase-2 and -8 and suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3, Nop30 multimerizes and binds to the splicing factor SRp30c and may act to influence alternative splice site selection in vivo.Synonyms: Apoptosis repressor with CARD, Muscle-enriched cytoplasmic protein, Myp, NOP, Nop30, Nucleolar protein 3, Nucleolar protein of 30 kDa

ID gène: 8996

UniProt: O60936