Occludin anticorps (C-Term)

N° du produit ABIN500409

Cité dans 3 publications. Cet anticorps anti-Occludin Polyclonal Lapin (ABIN500409) détecte spécifiquement Occludin dans WB, IF, IHC (p) et EIA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Occludin anticorps (C-Term) (ABIN500409)

Antigène: Occludin (OCLN)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Occludin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Occludin anticorps

Épitope: C-Term

Specificité: This antibody detectc OCLN.

Purification: Peptide affinity chromatography

Immunogène: OCLN antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human OCLN.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-Occludin (ABIN500409)

Ferguson, Kwak, Lim, Cesaire, Mills, Dalmage, Jones, Tarasov, Dyba, Robey, Yang, Simpson, Karim, Butcher, Gartrell, Gottesman, Jackson: "Angulin-1/LSR inhibition transiently disrupts the blood-tumor barrier to enhance doxil permeability and impair malignant glioma progression." dans: bioRxiv : the preprint server for biology, (2025) (PubMed).

Liang, Zhang, Deng, He, Liang, Liang, Chen, Tang, Chen, Yang: "The Potential Effect of Chinese Herbal Formula Hongqijiangzhi Fang in Improving NAFLD: Focusing on NLRP3 Inflammasome and Gut Microbiota." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 5378961, (2018) (PubMed).

Zhang, Tang, Deng, Chen, Liang, Xie, He, Chen, Yang: "Effects of shenling baizhu powder herbal formula on intestinal microbiota in high-fat diet-induced NAFLD rats." dans: Biomedicine & pharmacotherapy, Vol. 102, pp. 1025-1036, (2018) (PubMed).

Détails sur Occludin

Antigène: Occludin (OCLN)

Autre désignation: Occludin

Sujet: Tight junctions act as a semi-permeable barrier to the transport of ions, solutes, and water and are considered to function as a fence that divides apical and basolateral domains of plasma membranes. Tight junctions coordinate a variety of signaling and trafficking molecules regulating cell differentiation, proliferation, and polarity and contain a number of junctional proteins including Occludin, Claudins, junctional adhesion molecules (JAMs), as well as multiple scaffold proteins. Occludin, the first identified component of tight junction strands, is thought function as a signal transmitter in multiple signaling pathways and can associate with multiple kinases and phosphatases such as PI3-kinase and protein phosphatases 1 and 2A. At least two isoforms of OCLN are known to exist.Synonyms: OCLN

ID gène: 4950

UniProt: Q16625

Pathways: Cell-Cell Junction Organization, Hepatitis C